Pharmacokinetic study of artemether-lumefantrine given once daily for the treatment of uncomplicated multidrug-resistant falciparum malaria.

BACKGROUND: Adherence to antimalarial drug regimens is improved by simple dosing. If the fixed antimalarial drug combination artemether-lumefantrine (AL) could be given once daily, this should improve adherence and thus effectiveness and lower the risk of selecting for resistance. METHODS: In an op...

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Bibliographic Details
Main Authors: Ashley, E, Stepniewska, K, Lindegårdh, N, Mcgready, R, Annerberg, A, Hutagalung, R, Singtoroj, T, Hla, G, Brockman, A, Proux, S, Wilahphaingern, J, Singhasivanon, P, White, N, Nosten, F
Format: Journal article
Language:English
Published: 2007