MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia
<p>Aberrant enhancer activation is a key mechanism driving oncogene expression in many cancers. While much is known about the regulation of larger chromosome domains in eukaryotes, the details of enhancer-promoter interactions remain poorly understood. Recent work suggests co-activators like B...
المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , , , , , , , |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Springer Nature
2023
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