CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects.

HIV-1-specific cytotoxic T-lymphocyte (CTL) responses have been detected at a low frequency in many HIV-1-exposed, persistently seronegative (HEPS) subjects. However, it is unclear how CTLs could protect against HIV acquisition in HEPS subjects, when high levels of circulating CTL fail to prevent di...

Full description

Bibliographic Details
Main Authors: Kaul, R, Dong, T, Plummer, F, Kimani, J, Rostron, T, Kiama, P, Njagi, E, Irungu, E, Farah, B, Oyugi, J, Chakraborty, R, MacDonald, K, Bwayo, J, McMichael, A, Rowland-Jones, S
Format: Journal article
Language:English
Published: 2001