CD8(+) lymphocytes respond to different HIV epitopes in seronegative and infected subjects.

HIV-1-specific cytotoxic T-lymphocyte (CTL) responses have been detected at a low frequency in many HIV-1-exposed, persistently seronegative (HEPS) subjects. However, it is unclear how CTLs could protect against HIV acquisition in HEPS subjects, when high levels of circulating CTL fail to prevent di...

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Main Authors: Kaul, R, Dong, T, Plummer, F, Kimani, J, Rostron, T, Kiama, P, Njagi, E, Irungu, E, Farah, B, Oyugi, J, Chakraborty, R, MacDonald, K, Bwayo, J, McMichael, A, Rowland-Jones, S
格式: Journal article
语言:English
出版: 2001