A dual role for integrin-linked kinase in platelets: regulating integrin function and alpha-granule secretion.

Integrin-linked kinase (ILK) has been implicated in the regulation of a range of fundamental biological processes such as cell survival, growth, differentiation, and adhesion. In platelets ILK associates with beta1- and beta3-containing integrins, which are of paramount importance for the function o...

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Main Authors: Tucker, K, Sage, T, Stevens, J, Jordan, P, Jones, S, Barrett, N, St-Arnaud, R, Frampton, J, Dedhar, S, Gibbins, J
格式: Journal article
语言:English
出版: 2008