Translating ribosome affinity purification from C9orf72-associated amyotrophic lateral sclerosis patient-derived iPSC motor neurons
<p>The C9orf72 hexanucleotide repeat expansion [GGGGCC]<sub>n</sub> is the most common cause of familial amyotrophic lateral sclerosis. The endogenous role of the C9orf72 protein has not been fully characterised, nor how the presence of the repeat expansion affects downstream mecha...
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| Format: | Thesis |
| Language: | English |
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2019
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