Modulation of T-regulatory cells by small molecules: potential therapy for GvHD

Allogeneic haematopoietic stem cell transplantation (alloHSCT) is often curative for patients suffering from blood cancers. Nonetheless, significant morbidity and mortality are still prevalent. One major complication is graft versus host disease (GvHD) which occurs in 30-70% of patients. In this dis...