Transcriptional and epigenetic mechanisms of promiscuous gene expression by thymic epithelial cells
The thymus is the primary lymphoid organ responsible for the generation and selection of a T-cell repertoire that is able to respond to foreign antigens whilst remaining tolerant to self. For the purposes of T-cell central tolerance induction thymic epithelial cells (TEC) express almost all protein...
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| Format: | Thesis |
| Language: | English |
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2019
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