Transcriptional and epigenetic mechanisms of promiscuous gene expression by thymic epithelial cells

The thymus is the primary lymphoid organ responsible for the generation and selection of a T-cell repertoire that is able to respond to foreign antigens whilst remaining tolerant to self. For the purposes of T-cell central tolerance induction thymic epithelial cells (TEC) express almost all protein...

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Autore principale: Dhalla, F
Altri autori: Hollander, G
Natura: Tesi
Lingua:English
Pubblicazione: 2019
Soggetti:

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