Transcriptional and epigenetic mechanisms of promiscuous gene expression by thymic epithelial cells

The thymus is the primary lymphoid organ responsible for the generation and selection of a T-cell repertoire that is able to respond to foreign antigens whilst remaining tolerant to self. For the purposes of T-cell central tolerance induction thymic epithelial cells (TEC) express almost all protein...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Dhalla, F
مؤلفون آخرون: Hollander, G
التنسيق: أطروحة
اللغة:English
منشور في: 2019
الموضوعات: