Human papillomavirus DNA load and p16INK4a expression predict for local control in patients with anal squamous cell carcinoma treated with chemoradiotherapy.

As the detection rate of HPV-DNA in anal carcinoma commonly exceeds 90%, a comparison between sole HPV-positive and HPV-negative cancers with respect to treatment response following chemoradiotherapy (CRT) and long-term oncological outcome is challenging. Against this background, we aimed to assess...

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Bibliographic Details
Main Authors: Rödel, F, Wieland, U, Fraunholz, I, Kitz, J, Rave-Fränk, M, Wolff, H, Weiss, C, Wirtz, R, Balermpas, P, Fokas, E, Rödel, C
Format: Journal article
Language:English
Published: Wiley 2015