A metabolic sensor in action: News from the ATP-sensitive K+-channel

The KATP channel provides a link between metabolism and electrical activity in numerous cell types. It can be reconstituted by coexpression of two subunits, a pore-forming inward rectifier K+ channel and a regulatory subunit, the sulfonylurea receptor. Site-directed mutagenesis of these subunits ena...

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Bibliographic Details
Main Authors: Trapp, S, Ashcroft, F
Format: Journal article
Language:English
Published: 1997