Maternal activating KIRs protect against human reproductive failure mediated by fetal HLA-C2.

Many common disorders of pregnancy are attributed to insufficient invasion of the uterine lining by trophoblast, fetal cells that are the major cell type of the placenta. Interactions between fetal trophoblast and maternal uterine NK (uNK) cells--specifically interactions between HLA-C molecules exp...

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Bibliografiske detaljer
Main Authors: Hiby, SE, Apps, R, Sharkey, A, Farrell, L, Gardner, L, Mulder, A, Claas, F, Walker, J, Redman, C, Morgan, L, Tower, C, Regan, L, Moore, G, Carrington, M, Moffett, A
Format: Journal article
Sprog:English
Udgivet: 2010