Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape
Background. Antigen-specific CTL responses are thought to play a central role in containment of HIV-1 infection, but no consistent correlation has been found between the magnitude and/or breadth of response and viral load changes during disease progression. Methods and Findings. We undertook a detai...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Public Library of Science
2007
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