Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape

Sequential Broadening of CTL Responses in Early HIV-1 Infection Is Associated with Viral Escape

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Background. Antigen-specific CTL responses are thought to play a central role in containment of HIV-1 infection, but no consistent correlation has been found between the magnitude and/or breadth of response and viral load changes during disease progression. Methods and Findings. We undertook a detai...

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Bibliographic Details
Main Authors:	Karlsson, A, Iversen, A, Chapman, J, de Oliveira, T, Spotts, G, Mcmichael, A, Davenport, M, Hecht, F, Nixon, D
Format:	Journal article
Language:	English
Published:	Public Library of Science 2007

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