Investigation of haematopoietic cell growth and the impact of common mutations in myeloid malignancies
<p>The myelodysplastic syndromes (MDS) are disorders of the haematopoietic stem cell and are characterised by ineffective haematopoiesis. The TET2 and ASXL1 genes have been implicated to be important in the pathology of MDS, but their function has not yet been characterised as co-mutations in...
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| Format: | Thesis |
| Language: | English |
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2021
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