Uncoupling of virus-induced inflammation and anti-viral immunity in the brain parenchyma.
Non-neuroadapted influenza virus confined to the brain parenchyma does not induce antigen-specific immunity. Nevertheless, infection in this site upregulated major histocompatibility complex (MHC) class I and MHC class II expression and recruited lymphocytes to a perivascular compartment. T cells re...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2002
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