Differential thermostability and response to cystic fibrosis transmembrane conductance regulator (CFTR) potentiators of human and mouse F508del-CFTR

Cross-species comparative studies have highlighted differences between human and mouse cystic fibrosis transmembrane conductance regulator (CFTR), the epithelial Cl− channel defective in cystic fibrosis (CF). Here, we compare the impact of the most common CF mutation F508del on the function of human...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Bose, S, Bijvelds, M, Wang, Y, Liu, J, Cai, Z, Bot, A, De Jonge, H, Sheppard, D
स्वरूप: Journal article
भाषा:English
प्रकाशित: American Physiological Society 2019