Single nucleotide polymorphisms in the Toll-like receptor 3 and CD44 genes are associated with persistence of vaccine-induced immunity to the serogroup C meningococcal conjugate vaccine.

The rate of decay of antibody concentration following serogroup C meningococcal (MenC) polysaccharide-protein conjugate vaccination varies between individuals. This depends partly on vaccination age but may be influenced by human genetics. We studied 721 single nucleotide polymorphisms (SNPs) across...

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Bibliographic Details
Main Authors: Moore, C, Hennig, B, Perrett, K, Hoe, J, Lee, S, Fletcher, H, Brocklebank, D, O'Connor, D, Snape, MD, Hall, A, Segal, S, Hill, A, Pollard, A
Format: Journal article
Language:English
Published: 2012