How many specific B cells are needed to protect against a virus?

How many specific B cells are needed to protect against a virus?

The size of the Ab repertoire has been estimated to comprise theoretically somewhere between > 10(10) and approximately 10(4) specificities, dependent on the criteria used. In an attempt to estimate the anti-viral protective Ab repertoire of the mouse the B cell and Ab-forming cell (AFC) freq...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Bachmann, M, Kündig, T, Kalberer, C, Hengartner, H, Zinkernagel, R
التنسيق:	Journal article
اللغة:	English
منشور في:	1994

مواد مشابهة

Formalin inactivation of vesicular stomatitis virus impairs T-cell- but not T-help-independent B-cell responses.
حسب: Bachmann, M, وآخرون
منشور في: (1993)

Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"?
حسب: Bachmann, M, وآخرون
منشور في: (1997)

T helper cell-independent neutralizing B cell response against vesicular stomatitis virus: role of antigen patterns in B cell induction?
حسب: Bachmann, M, وآخرون
منشور في: (1995)

Fewer protective cytotoxic T-cell epitopes than T-helper-cell epitopes on vesicular stomatitis virus.
حسب: Kündig, T, وآخرون
منشور في: (1993)

Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells.
حسب: Bachmann, M, وآخرون
منشور في: (1994)

T cells and memory lapses - Response
حسب: Zinkernagel, R, وآخرون
منشور في: (1997)

Nonimmunogenic tumor cells may efficiently restimulate tumor antigen-specific cytotoxic T cells.
حسب: Kündig, T, وآخرون
منشور في: (1993)

T-independent activation of B cells by vesicular stomatitis virus: no evidence for the need of a second signal.
حسب: Fehr, T, وآخرون
منشور في: (1996)

The influence of antigen organization on B cell responsiveness.
حسب: Bachmann, M, وآخرون
منشور في: (1993)

Regulation of IgG antibody titers by the amount persisting of immune-complexed antigen.
حسب: Bachmann, M, وآخرون
منشور في: (1994)

On the role of antigen in maintaining cytotoxic T-cell memory.
حسب: Kündig, T, وآخرون
منشور في: (1996)

Induction of protective cytotoxic T cells with viral proteins.
حسب: Bachmann, M, وآخرون
منشور في: (1994)

Induction of protective cytotoxic T cells with viral proteins
حسب: Bachmann, M, وآخرون
منشور في: (1994)

Immunopathology or organ-specific autoimmunity as a consequence of virus infection.
حسب: Aichele, P, وآخرون
منشور في: (1996)

Virus-induced humoral immunity: on how B cell responses are initiated.
حسب: Zabel, F, وآخرون
منشور في: (2013)

Virus-induced humoral immunity: On how B cell responses are initiated
حسب: Zabel, F, وآخرون
منشور في: (2013)

On T Cell Memory: Arguments for Antigen Dependence
حسب: Kündig, T, وآخرون
منشور في: (1996)

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حسب: Kündig, T, وآخرون
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Virus-specific MHC-class II-restricted TCR-transgenic mice: effects on humoral and cellular immune responses after viral infection.
حسب: Oxenius, A, وآخرون
منشور في: (1998)

On immunological memory.
حسب: Zinkernagel, R, وآخرون
منشور في: (1996)

Comparison of the sensitivity of in vivo and in vitro assays for detection of antiviral cytotoxic T cell activity.
حسب: Castelmur, I, وآخرون
منشور في: (1993)

EPITOPE REPETITIVENESS AS A SELF NONSELF DISCRIMINATOR FOR B-CELLS
حسب: Bachmann, M, وآخرون
منشور في: (1995)

Immune responses in interleukin-2-deficient mice.
حسب: Kündig, T, وآخرون
منشور في: (1993)

THE NEUTRALIZING ANTIBODY-RESPONSE AGAINST VESICULAR STOMATITIS-VIRUS
حسب: Zinkernagel, R, وآخرون
منشور في: (1995)

Immunization with recombinant protein: conditions for cytotoxic T cell and/or antibody induction.
حسب: Bachmann, M, وآخرون
منشور في: (1994)

"Negative vaccination" by specific CD4 T cell tolerisation enhances virus-specific protective antibody responses.
حسب: Karl S Lang, وآخرون
منشور في: (2007-01-01)

T-cell independent IgM and enduring protective IgG antibodies induced by chimeric measles viruses.
حسب: Fehr, T, وآخرون
منشور في: (1998)

Impairment of CD4(+) T cell responses during chronic virus infection prevents neutralizing antibody responses against virus escape mutants.
حسب: Ciurea, A, وآخرون
منشور في: (2001)

Allergen-specific immunotherapy: regulatory T cells or allergen-specific IgG?
حسب: Kündig, T, وآخرون
منشور في: (2010)

Vesicular stomatitis virus Indiana glycoprotein as a T-cell-dependent and -independent antigen.
حسب: Freer, G, وآخرون
منشور في: (1994)

Peripheral T cells in mice lacking p56lck do not express significant antiviral effector functions.
حسب: Molina, T, وآخرون
منشور في: (1993)

Characterizing Protease Specificity: How Many Substrates Do We Need?
حسب: Michael Schauperl, وآخرون
منشور في: (2015-01-01)

In vivo versus in vitro assays for assessment of T- and B- cell function.
حسب: Bachmann, M, وآخرون
منشور في: (1994)

How many T cells help one B cell?
حسب: Waldmann, H, وآخرون
منشور في: (1980)

A non-retroviral RNA virus persists in DNA form.
حسب: Klenerman, P, وآخرون
منشور في: (1997)

Immunity to viruses in B cell-deficient mice: influence of antibodies on virus persistence and on T cell memory.
حسب: Bründler, M, وآخرون
منشور في: (1996)

Neutralizing antiviral B cell responses.
حسب: Bachmann, M, وآخرون
منشور في: (1997)

CD4(+) T cell subsets during virus infection. Protective capacity depends on effector cytokine secretion and on migratory capability.
حسب: Maloy, K, وآخرون
منشور في: (2000)

CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions.
حسب: Oxenius, A, وآخرون
منشور في: (1996)

Immunogenicity of a viral model vaccine after different inactivation procedures.
حسب: Bachmann, M, وآخرون
منشور في: (1994)