Characterisation of a novel mouse model of mitochondrial disease – a hypomorphic Wars2 ENU-induced allele
<p>Mitochondrial aminoacyl-tRNA synthetases (mtRS) are vital for mitochondrial translation. mtRSs catalyse the aminoacylation of mitochondrial tRNA with their cognate amino acid. Mutations in mtRS genes are associated with distinct clinical pathologies in humans. Studying mtRS mutations in mod...
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| Format: | Thesis |
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2017
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