Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors

STING is an innate immune cytosolic adaptor for DNA sensors that engage malaria parasite (Plasmodium falciparum) or other pathogen DNA. As P. falciparum infects red blood cells and not leukocytes, how parasite DNA reaches such host cytosolic DNA sensors in immune cells is unclear. Here we show that...

Полное описание

Библиографические подробности
Главные авторы:	Sisquella, X, Ofir-Birin, Y, Pimentel, M, Cheng, L, Abou Karam, P, Sampaio, N, Penington, J, Connolly, D, Giladi, T, Scicluna, B, Sharples, R, Waltmann, A, Avni, D, Schwartz, E, Schofield, L, Porat, Z, Hansen, D, Papenfuss, A, Eriksson, E, Gerlic, M, Hill, A, Bowie, A, Regev-Rudzki, N
Формат:	Journal article
Язык:	English
Опубликовано:	Nature Publishing Group 2017

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