A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis.

A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis.

Type 2 innate lymphoid cells (ILC2s, nuocytes, NHC) require RORA and GATA3 for their development. We show that human ILC2s express skin homing receptors and infiltrate the skin after allergen challenge, where they produce the type 2 cytokines IL-5 and IL-13. Skin-derived ILC2s express the IL-33 rece...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Salimi, M, Barlow, J, Saunders, S, Xue, L, Gutowska-Owsiak, D, Wang, X, Huang, L, Johnson, D, Scanlon, S, McKenzie, A, Fallon, P, Ogg, G
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Rockefeller University Press. 2013

Ижил төстэй зүйлс

The role of type 2 innate lymphoid cells in the pathogenesis of atopic dermatitis
-н: Salimi, M, зэрэг
Хэвлэсэн: (2014)

Proof-of-concept clinical trial of etokimab shows a key role for IL-33 in atopic dermatitis pathogenesis
-н: Chen, Y, зэрэг
Хэвлэсэн: (2019)

IL-17A and IL-22 cause down-regulation of filaggrin - implications for the pathogenesis of atopic eczema
-н: Gutowska-Owsiak, D, зэрэг
Хэвлэсэн: (2010)

Interleukin-22-mediated downregulation of filaggrin expression in keratinocytes is an important mechanism in pathogenesis of atopic dermatitis
-н: Gutowska-Owsiak, D, зэрэг
Хэвлэсэн: (2010)

Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity.
-н: Saunders, S, зэрэг
Хэвлэсэн: (2015)

IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent
-н: Hardman, CS, зэрэг
Хэвлэсэн: (2021)

Association between IL-25, IL-33 and atopic dermatitis: A systematic review and meta-analysis
-н: Boyang Zhou, зэрэг
Хэвлэсэн: (2023-06-01)

Association between polymorphisms of <i>IL33</i> and <i>IL37</i> and atopic dermatitis
-н: O. A. Svitich, зэрэг
Хэвлэсэн: (2024-11-01)

IL-33, IL-25, and TSLP induce a distinct phenotypic and activation profile in human type 2 innate lymphoid cells
-н: Ana Camelo, зэрэг
Хэвлэсэн: (2017-04-01)

IL-33 activates group 2 innate lymphoid cell expansion and modulates endometriosis
-н: Jessica E. Miller, зэрэг
Хэвлэсэн: (2021-12-01)

Innate lymphoid cells: a new key player in atopic dermatitis
-н: Haiping Jia, зэрэг
Хэвлэсэн: (2023-10-01)

IL-22 in Atopic Dermatitis
-н: Julia Laska, зэрэг
Хэвлэсэн: (2024-08-01)

Identification and functional analysis of type 2 innate lymphoid cells in the skin and in lesional skin biopsies of patients with atopic dermatitis
-н: Salimi, M
Хэвлэсэн: (2014)

IL-33-induced keratoconjunctivitis is mediated by group 2 innate lymphoid cells in mice
-н: Yuka Hosotani, зэрэг
Хэвлэсэн: (2023-04-01)

Emerging roles for IL-25 and IL-33 in colorectal cancer tumorigenesis
-н: Eric Jou, зэрэг
Хэвлэсэн: (2022-10-01)

IL-17 downregulates filaggrin and affects keratinocyte expression of genes associated with cellular adhesion.
-н: Gutowska-Owsiak, D, зэрэг
Хэвлэсэн: (2012)

IL-17 influences expression of genes associated with barrier function in keratinocytes
-н: Gutowska-Owsiak, D, зэрэг
Хэвлэсэн: (2011)

Activation of eosinophils interacting with dermal fibroblasts by pruritogenic cytokine IL-31 and alarmin IL-33: implications in atopic dermatitis.
-н: Chun-Kwok Wong, зэрэг
Хэвлэсэн: (2012-01-01)

IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
-н: Alyse L. Frisbee, зэрэг
Хэвлэсэн: (2019-06-01)

IL-33 promotes innate lymphoid cell-dependent IFN-γ production required for innate immunity to Toxoplasma gondii
-н: Joseph T Clark, зэрэг
Хэвлэсэн: (2021-04-01)

MHCII-mediated dialog between group 2 innate lymphoid cells and CD4(+) T cells potentiates type 2 immunity and promotes parasitic helminth expulsion.
-н: Oliphant, C, зэрэг
Хэвлэсэн: (2016)

Microbiota and IL-33/31 Axis Linkage: Implications and Therapeutic Perspectives in Atopic Dermatitis and Psoriasis
-н: Laura Bonzano, зэрэг
Хэвлэсэн: (2023-07-01)

Evaluation of innate lymphoid cells and their subsets in atopic dermatitis patients with and without dupilumab therapy
-н: Jarmila Čelakovská, зэрэг
Хэвлэсэн: (2024-12-01)

Dupilumab Effects on Innate Lymphoid Cell and Helper T Cell Populations in Patients with Atopic Dermatitis
-н: Yasutomo Imai, зэрэг
Хэвлэсэн: (2021-03-01)

Group 2 innate lymphoid cells express functional NKp30 receptor inducing type 2 cytokine production
-н: Ogg, G, зэрэг
Хэвлэсэн: (2015)

Interleukin-17 and interleukin-22 contribute to alterations in epidermal function via multiple pathways - role in atopic eczema
-н: Gutowska-Owsiak, D, зэрэг
Хэвлэсэн: (2011)

Pathogenetic role of IL-4 and IL-13 in atopic dermatitis: The inhibitory pathways
-н: D. Sh. Macharadze
Хэвлэсэн: (2025-03-01)

CD1a presentation of endogenous antigens by group 2 innate lymphoid cells
-н: Hardman, C, зэрэг
Хэвлэсэн: (2017)

Group 2 innate lymphoid cells express functional NKp30 receptor inducing type 2 cytokine production
-н: Salimi, M, зэрэг
Хэвлэсэн: (2015)

Potential Role of IL-37 in Atopic Dermatitis
-н: Alicja Mesjasz, зэрэг
Хэвлэсэн: (2023-12-01)

Targeting IL-4 for the Treatment of Atopic Dermatitis
-н: Chiricozzi A, зэрэг
Хэвлэсэн: (2020-09-01)

Interleukin-17 mediates adhesion impairment in human keratinocytes - potential involvement in barrier dysfunction during atopic skin inflammation
-н: Gutowska-Owsiak, D, зэрэг
Хэвлэсэн: (2012)

IL-33/13 Axis and IL-4/31 Axis Play Distinct Roles in Inflammatory Process and Itch in Psoriasis and Atopic Dermatitis
-н: Bodoor K, зэрэг
Хэвлэсэн: (2020-06-01)

P41 IL-33-MEDIATED EXPANSION OF TYPE 2 INNATE LYMPHOID CELLS AMELIORATES PROGRESSIVE GLOMERULOSCLEROSIS
-н: M. Becker, зэрэг
Хэвлэсэн: (2016-11-01)

The histamine-synthesizing enzyme histidine decarboxylase is upregulated by keratinocytes in atopic skin.
-н: Gutowska-Owsiak, D, зэрэг
Хэвлэсэн: (2014)

Expression of histamine-synthesizing enzyme, histidine decarboxylase, by keratinocytes and its regulation by cytokines and factors relevant to atopic skin disease
-н: Gutowska-Owsiak, D, зэрэг
Хэвлэсэн: (2013)

Selective IL-13 inhibitors for the treatment of atopic dermatitis
-н: Francisca Gonçalves, зэрэг
Хэвлэсэн: (2021-03-01)

Severe atopic dermatitis is associated with a reduced frequency of IL-10 producing allergen-specific CD4+ T cells.
-н: Seneviratne, S, зэрэг
Хэвлэсэн: (2006)

STING activation in alveolar macrophages and group 2 innate lymphoid cells suppresses IL-33–driven type 2 immunopathology
-н: Li She, зэрэг
Хэвлэсэн: (2021-02-01)

Serum Levels of Il-8, Tnf-α And Il-6 in Children with Atopic Dermatitis
-н: Perihan Öztürk, зэрэг
Хэвлэсэн: (2012-08-01)