Drugs and renal insufficiency

Renal insufficiency alters both the disposition of drugs in the body (pharmacokinetics) and tissue responses to drugs (pharmacodynamics). If drugs or their active metabolites are excreted by the kidneys they can accumulate in renal insufficiency and cause adverse effects. Using simple principles, on...

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Bibliographic Details
Main Author: Aronson, J
Format: Journal article
Language:English
Published: 2007