Inhibition of glycogen breakdown by imino sugars in vitro and in vivo.

The imino sugar N-butyldeoxynojirimycin (NB-DNJ) is a glucose analogue which inhibits the glycoprotein N-glycan processing enzymes alpha-glucosidases I and II and the ceramide glucosyltransferase that catalyses the first step of glycosphingolipid biosynthesis. This and other N-alkylated DNJ compound...

Full description

Bibliographic Details
Main Authors: Andersson, U, Reinkensmeier, G, Butters, T, Dwek, R, Platt, F
Format: Journal article
Language:English
Published: 2004