Random mutagenesis screening indicates the absence of a separate H(+)-sensor in the pH-sensitive Kir channels.

Several inwardly-rectifying (Kir) potassium channels (Kir1.1, Kir4.1 and Kir4.2) are characterised by their sensitivity to inhibition by intracellular H(+) within the physiological range. The mechanism by which these channels are regulated by intracellular pH has been the subject of intense scrutiny...

詳細記述

書誌詳細
主要な著者: Paynter, J, Shang, L, Bollepalli, M, Baukrowitz, T, Tucker, S
フォーマット: Journal article
言語:English
出版事項: 2010