Transcription-driven genome organization: a model for chromosome structure and the regulation of gene expression tested through simulation
Current models for the folding of the human genome see a hierarchy stretching down from chromosome territories, through A/B compartments and topologically-associating domains (TADs), to contact domains stabilized by cohesin and CTCF. However, molecular mechanisms underlying this folding, and the way...
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| Format: | Journal article |
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Oxford University Press
2018
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