Tandem differential mobility analysis-mass spectrometry reveals partial gas-phase collapse of the GroEL complex.

A parallel-plate differential mobility analyzer and a time-of-flight mass spectrometer (DMA-MS) are used in series to measure true mobility in dry atmospheric pressure air for mass-resolved electrosprayed GroEL tetradecamers (14-mers; ~800 kDa). Narrow mobility peaks are found (2.6-2.9% fwhm); hence...

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Bibliographic Details
Main Authors: Hogan, C, Ruotolo, B, Robinson, C, Fernandez de la Mora, J
Format: Journal article
Language:English
Published: 2011