The structure of CrgA from Neisseria meningitidis reveals a new octameric assembly state for LysR transcriptional regulators.

LysR-type transcriptional regulators (LTTRs) form the largest family of bacterial regulators acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes. The LTTR, CrgA, from the human pathogen Neisseria meningitidis, is upr...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Sainsbury, S, Lane, L, Ren, J, Gilbert, R, Saunders, N, Robinson, C, Stuart, D, Owens, R
Format: Journal article
Sprache:English
Veröffentlicht: 2009