Development of novel molecular probes to study cellular behaviour using NMR: i) Development of a novel 19F NMR probe to monitor the dynamic self-assembly of high molecular weight proteins in cells ii) Mechanistic analysis of lipoamide as a potential ALS drug by stable isotope labelling and quantitative NMR
<p>This DPhil thesis describes the novel analytical methodologies developed by the author using biomolecular Nuclear Magnetic Resonance (NMR) spectroscopy. These new bio-NMR methods address the current limitations in modern NMR spectroscopy and can be used to study the structure and dynamics o...
1. Verfasser: | |
---|---|
Weitere Verfasser: | |
Format: | Abschlussarbeit |
Sprache: | English |
Veröffentlicht: |
2023
|
Schlagworte: |