Development of novel molecular probes to study cellular behaviour using NMR: i) Development of a novel 19F NMR probe to monitor the dynamic self-assembly of high molecular weight proteins in cells ii) Mechanistic analysis of lipoamide as a potential ALS drug by stable isotope labelling and quantitative NMR

<p>This DPhil thesis describes the novel analytical methodologies developed by the author using biomolecular Nuclear Magnetic Resonance (NMR) spectroscopy. These new bio-NMR methods address the current limitations in modern NMR spectroscopy and can be used to study the structure and dynamics o...

Ausführliche Beschreibung

Bibliographische Detailangaben
1. Verfasser: Kishigami, S
Weitere Verfasser: Casablancas Antras, V
Format: Abschlussarbeit
Sprache:English
Veröffentlicht: 2023
Schlagworte: