Development of novel molecular probes to study cellular behaviour using NMR: i) Development of a novel 19F NMR probe to monitor the dynamic self-assembly of high molecular weight proteins in cells ii) Mechanistic analysis of lipoamide as a potential ALS drug by stable isotope labelling and quantitative NMR
<p>This DPhil thesis describes the novel analytical methodologies developed by the author using biomolecular Nuclear Magnetic Resonance (NMR) spectroscopy. These new bio-NMR methods address the current limitations in modern NMR spectroscopy and can be used to study the structure and dynamics o...
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| Format: | Thesis |
| Language: | English |
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2023
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