The genetic engineering of monoclonal antibodies.

A number of recent technological developments have greatly facilitated the genetic engineering of immunoglobulins. The use of PCR has permitted the variable regions to be rapidly cloned either from a specific hybridoma source or as a gene library from non-immunised cells. The conversion of the roden...

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Bibliographic Details
Main Authors: Owens, R, Young, R
Format: Journal article
Language:English
Published: 1994