A copper(I)-catalyzed addition/annulation sequence for the two-component synthesis of γ-ylidenebutenolides
A highly efficient Cu(I)-catalyzed addition/annulation sequence has been developed for the synthesis of (Z)- ylidenebutenolides employing readily available α-ketoacids and alkynes as substrates. The reactions employ a simple commercially available Cu(I)-catalyst, display good substrate sc...
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Format: | Journal article |
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American Chemical Society
2017
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