Secreted and transmembrane 1A is a novel co-stimulatory ligand

Most T cell responses to pathogens or self antigens are modulated through the action of regulatory T cells and tissue-specific inhibitory mechanisms. To this end, several receptor-ligand pairs have evolved which either augment or diminish T cell function. Here we describe the tissue ligand SECTM1A (...

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Bibliographic Details
Main Authors: Howie, D, Garcia Rueda, H, Brown, M, Waldmann, H
Format: Journal article
Language:English
Published: Public Library of Science 2013