Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5.

RecQ helicases are important maintainers of genome integrity with distinct roles in almost every cellular process requiring access to DNA. RECQL5 is one of five human RecQ proteins and is particularly versatile in this regard, forming protein complexes with a diverse set of cellular partners in orde...

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Bibliographic Details
Main Authors: Newman, J, Aitkenhead, H, Savitsky, P, Gileadi, O
Format: Journal article
Language:English
Published: Oxford University Press 2017