Phenotypic characterization of HIV-specific CD8+ T cells during early and chronic infant HIV-1 infection.

Although CD8(+) T cells play an important role in the containment of adult HIV-1 replication, their role in infant HIV-1 infection is not as well understood. Impaired HIV-specific CD8(+) T cell responses may underlie the persistently high viral loads observed in infants. We examined the frequency an...

Full description

Bibliographic Details
Main Authors: Slyker, J, John-Stewart, G, Dong, T, Lohman-Payne, B, Reilly, M, Atzberger, A, Taylor, S, Maleche-Obimbo, E, Mbori-Ngacha, D, Rowland-Jones, S
Format: Journal article
Language:English
Published: Public Library of Science 2011