Correlating tau pathology to brain atrophyusing a physics-based Bayesian model

Misfolded tau proteins are a classical hallmark of Alzheimer’s disease. Increasing evidence indicates that tau–and not amyloid–is the main agent in driving neurodegeneration and tissue atrophy in Alzheimer’s brains. However, the precise correlation between tau and atrophy remains insufficiently unde...

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Bibliographic Details
Main Authors: Schafer, A, Chaggar, P, Goriely, A, Kuhl, E
Other Authors: Alzheimer’s Disease Neuroimaging Initiative
Format: Journal article
Language:English
Published: Springer 2022