Auto-antibodies to the receptor tyrosine kinase MuSK in patients with myasthenia gravis without acetylcholine receptor antibodies.

Myasthenia gravis (MG) is an antibody-mediated autoimmune disease of the neuromuscular junction. In approximately 80% of patients, auto-antibodies to the muscle nicotinic acetylcholine receptor (AChR) are present. These antibodies cause loss of AChR numbers and function, and lead to failure of neuro...

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Detalles Bibliográficos
Autores principales: Hoch, W, McConville, J, Helms, S, Newsom-Davis, J, Melms, A, Vincent, A
Formato: Journal article
Lenguaje:English
Publicado: 2001