1,25-Dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line.

Inducible synthesis of nitric oxide (NO) by macrophages is an important mechanism of the host defense against intracellular infection in mice, but the evidence for significant levels of inducible NO production by human macrophages is controversial. Here we report that the human promyelocytic cell li...

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Bibliographic Details
Main Authors: Rockett, K, Brookes, R, Udalova, I, Vidal, V, Hill, A, Kwiatkowski, D
Format: Journal article
Language:English
Published: 1998