FOXP3+ regulatory T cells as biomarkers in human malignancies.
BACKGROUND: Regulatory T cells (Treg) expressing the FOXP3 forkhead transcription factor maintain immunological self-tolerance and can enable tumour cells to escape immunosurveillance. OBJECTIVE: To provide an overview of studies using FOXP3 as a biomarker in human malignancies, particularly in the...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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