FOXP3+ regulatory T cells as biomarkers in human malignancies.
BACKGROUND: Regulatory T cells (Treg) expressing the FOXP3 forkhead transcription factor maintain immunological self-tolerance and can enable tumour cells to escape immunosurveillance. OBJECTIVE: To provide an overview of studies using FOXP3 as a biomarker in human malignancies, particularly in the...
| Hauptverfasser: | , |
|---|---|
| Format: | Journal article |
| Sprache: | English |
| Veröffentlicht: |
2008
|