Developing inhibitors of bromodomain-histone interactions

<p>Lysine acetylation is a widespread protein post-translational modification that influences diverse cellular processes. An association between acetylation of histone N-terminal tails and transcriptional activation has been recognised since the 1960s. However, it has only become apparent sinc...

Ausführliche Beschreibung

Bibliographische Detailangaben
1. Verfasser: Hewings, D
Weitere Verfasser: Conway, S
Format: Abschlussarbeit
Sprache:English
Veröffentlicht: 2014
Schlagworte: