Developing inhibitors of bromodomain-histone interactions

Developing inhibitors of bromodomain-histone interactions

<p>Lysine acetylation is a widespread protein post-translational modification that influences diverse cellular processes. An association between acetylation of histone N-terminal tails and transcriptional activation has been recognised since the 1960s. However, it has only become apparent sinc...

書誌詳細
第一著者:	Hewings, D
その他の著者:	Conway, S
フォーマット:	学位論文
言語:	English
出版事項:	2014
主題:	Chemical biology Physical Sciences Organic chemistry Organic synthesis Chemistry & allied sciences

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