Developing inhibitors of bromodomain-histone interactions
<p>Lysine acetylation is a widespread protein post-translational modification that influences diverse cellular processes. An association between acetylation of histone N-terminal tails and transcriptional activation has been recognised since the 1960s. However, it has only become apparent sinc...
Autor principal: | Hewings, D |
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Outros Autores: | Conway, S |
Formato: | Thesis |
Idioma: | English |
Publicado em: |
2014
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Assuntos: |
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