Developing inhibitors of bromodomain-histone interactions

<p>Lysine acetylation is a widespread protein post-translational modification that influences diverse cellular processes. An association between acetylation of histone N-terminal tails and transcriptional activation has been recognised since the 1960s. However, it has only become apparent sinc...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Hewings, D
مؤلفون آخرون: Conway, S
التنسيق: أطروحة
اللغة:English
منشور في: 2014
الموضوعات: