Oncometabolite induced primary cilia loss in pheochromocytoma
Primary cilia are sensory organelles involved in regulation of cellular signaling. Cilia loss is frequently observed in tumors; yet, the responsible mechanisms and consequences for tumorigenesis remain unclear. We demonstrate that cilia structure and function is disrupted in human pheochromocytomas...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Bioscientifica
2019
|