Expression and functional characterization of FOXP3+ CD4+ regulatory T cells in ulcerative colitis.
BACKGROUND: CD4+CD25+ regulatory T cells (TR) can prevent or treat experimental murine colitis but little is known about their potential role in human inflammatory bowel disease (IBD). FOXP3 is a transcription factor that plays a critical role in the development and function of CD4+CD25+ TR. The ai...
Hlavní autoři: | Yu, Q, Saruta, M, Avanesyan, A, Fleshner, P, Banham, A, Papadakis, K |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2007
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