Alternating access mechanism in the POT family of oligopeptide transporters.

Short chain peptides are actively transported across membranes as an efficient route for dietary protein absorption and for maintaining cellular homeostasis. In mammals, peptide transport occurs via PepT1 and PepT2, which belong to the proton-dependent oligopeptide transporter, or POT family. The re...

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Bibliographic Details
Main Authors: Solcan, N, Kwok, J, Fowler, P, Cameron, A, Drew, D, Iwata, S, Newstead, S
Format: Journal article
Language:English
Published: 2012