The role of LATS1 in DNA damage signalling

<p>Genomic DNA is constantly exposed to assaults, which if not dealt with, can lead to genomic instability and carcinogenesis. In response to stress including either Ionising Radiation (IR) or replication stress, ATM and ATR promote the activation of cell cycle checkpoints and initiate repair...

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Bibliographic Details
Main Author: Latusek, R
Other Authors: O'Neill, E
Format: Thesis
Language:English
Published: 2012
Subjects: