Redirecting the cellular information flow with programmable dCas9-based chimeric receptors
<p>Signal integration and transduction by cell-surface receptors is a complex, multi-layered process resulting in tight regulation of downstream mediators, which in turn elicit pre-defined native cellular responses. The modular architecture of transmembrane receptors provides a unique opportun...
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| Format: | Thesis |
| Language: | English |
| Published: |
2018
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