Hypoxia inducible factor 1alpha and 2alpha overexpression in inflammatory bowel disease.

AIMS: Hypoxia inducible factors 1alpha and 2alpha (HIF1alpha and HIF2alpha) are hypoxia regulated transcriptional factors, which control the expression of a variety of genes responsible for angiogenesis, glycolysis, and the inhibition of apoptosis. Because angiogenesis and tissue regeneration are i...

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Bibliographic Details
Main Authors: Giatromanolaki, A, Sivridis, E, Maltezos, E, Papazoglou, D, Simopoulos, C, Gatter, K, Harris, A, Koukourakis, M
Format: Journal article
Language:English
Published: 2003